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AKT1 — LIMS1

Pathways - manually collected, often from reviews:

• NCI Pathway Database Integrin-linked kinase signaling: ILK/PINCH1/alpha parvin complex (ILK-LIMS1-PARVA) → AKT1 (AKT1) (modification, inhibits) Wu et al., J Cell Sci 1999*, Attwell et al., Oncogene 2000*, Persad et al., J Biol Chem 2001, Fukuda et al., J Biol Chem 2003, Qian et al., Oncogene 2005*, Wilson et al., Biochem J 2005*, Joshi et al., FASEB J 2007*, Delcommenne et al., Proc Natl Acad Sci U S A 1998
  Evidence: mutant phenotype, assay

Text-mined interactions from Literome

Fukuda et al., J Biol Chem 2003 : Third, PINCH-1 and ILK are required for optimal activating phosphorylation of PKB/Akt , an important signaling intermediate of the survival pathway ... Third, PINCH-1 and ILK are required for optimal activating phosphorylation of PKB/Akt , an important signaling intermediate of the survival pathway
Eke et al., J Clin Invest 2010 (Neoplasms) : PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha