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MUC16 — SLC22A3

Text-mined interactions from Literome

Comamala et al., Br J Cancer 2011 (Carcinoma...) : The role of CA125/MUC16 in EMT was investigated using single-chain antibody mediated knockdown of cell surface CA125/MUC16 in overexpressing EOC NIH : OVCAR3 cells ... Our findings suggest that CA125/MUC16 plays a role in EMT , presumably through its interaction with E-cadherin and ß-catenin complexes and by modulating EGFR and its downstream signalling pathway in NIH : OVCAR3 cells
Fujii et al., Cancer Sci 2013 (Disease Progression...) : This study demonstrates that ALKBH2 is an upstream molecule of the oncoprotein, MUC1 , and regulates cell cycle and EMT , resulting in progression of urothelial carcinomas