Duan et al., Exp Neurol 2000
(Nerve Degeneration) :
Exposure of cultured primary striatal neurons to 3NP induced a rapid increase of Par-4 levels and caspase activation
Lu et al., Zhonghua Er Ke Za Zhi 2008
:
And the relative Caspase-3 activity which was enhanced by the treatment with glutamate ( 0.1428 +/- 0.0495 and 0.8616 +/- 0.1051, P < 0.01 ), was suppressed by Par-4-SiRNA-1 and Par-4-SiRNA-2 ( 0.8616 +/- 0.1051 and 0.6581 +/- 0.0555, respectively, P < 0.01 )