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CREB3 — SP1
Pathways - manually collected, often from reviews:
-
FastForward regulation:
SP1
→
CREB3
(transcriptional regulation, unknown)
Evidence: DNABINDING
Text-mined interactions from Literome
Shell et al., Biol Reprod 2002
:
Regulation of cyclic adenosine 3',5'-monophosphate response element binding protein (
CREB ) expression by
Sp1 in the mammalian testis ... Furthermore,
CREB promoter activity was
induced over 70-fold by transient overexpression of
Sp1 in SL2 cells, suggesting that Sp1 is an important regulator of CREB expression
Hilton et al., Virology 1995
:
In contrast, ICP8 mutant infected cells contained elevated amounts of NF kappa B activity equivalent to WT virus, no
induction of
Sp1 relative to WT virus, and reduced
ATF/CREB activity relative to WT virus