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MAFB — MYLIP
Text-mined interactions from Literome
Rio-Machin et al., Leukemia 2013
(Multiple Myeloma...) :
We found that target genes of the most differentially expressed miRNAs are directly involved in the pathogenesis of MM ; specifically, the inhibition of hsa-miR-425, hsa-miR-152 and
hsa-miR-24 , which are all downregulated in h-MM,
leads to the overexpression of CCND1, TACC3,
MAFB , FGFR3 and MYC, which are the also the oncogenes upregulated by the most frequent IgH chromosomal translocations occurring in nh-MM. Importantly, we showed that the downregulation of these specific miRNAs and the upregulation of their targets also occur simultaneously in primary cases of h-MM
Cheng et al., J Bone Miner Res 2013
(Lupus Erythematosus, Systemic) :
miR-148a directly targeted MAFB mRNA by binding to the 3 ' untranslated region ( 3'UTR ) and
repressed MAFB protein expression
Barbagallo et al., BMC genomics 2013
:
Our computational analysis suggests that
MAFB ( a transcription factor exclusively expressed in pancreatic a cells within adult rodent islets of Langerhans )
controls the expression of
miR-296-3p and miR-298-5p