Gene interactions and pathways from curated databases and text-mining

◀ Back to HIF1A

CCND1 — HIF1A

Text-mined interactions from Literome

Ouyang et al., J Cell Physiol 2009 : Moreover, the soluble nickel induced cyclin D1 degradation is dependent on its Thr286 residue and requires IKKalpha, but not HIF-1alpha , which are both reported to be involved in cyclin D1 down-regulation
Yang et al., Cancer Res 2010 (Breast Neoplasms) : Here, we show the histone demethylase JMJD2B is regulated by both ERalpha and HIF-1alpha , drives breast cancer cell proliferation in normoxia and hypoxia, and epigenetically regulates the expression of cell cycle genes such as CCND1 , CCNA1, and WEE1