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NOTCH3 — PARP1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 248 proteins (association, pull down) von Eyss et al., EMBO J 2012

Text-mined interactions from Literome

Wang et al., Blood 2008 (Leukemia-Lymphoma, Adult T-Cell) : The results suggested that deregulated constitutive Rap1 activation caused abnormal expansion of DP thymocytes, bypassing the pre-T-cell receptor and eventually leading to Notch1 mutations and Notch dependent T-ALL
Kannan et al., Blood 2011 (Precursor B-Cell Lymphoblastic Leukemia-Lymphoma...) : Notch/HES1 mediated PARP1 activation : a cell type-specific mechanism for tumor suppression