◀ Back to MAPK14

MAPK14 — SYN1

Text-mined interactions from Literome

Jovanovic et al., Nat Neurosci 2000 (MAP Kinase Signaling System...) : In a synaptosomal preparation, brain derived neurotrophic factor (BDNF) increased mitogen activated protein ( MAP ) kinase dependent synapsin I phosphorylation and acutely facilitated evoked glutamate release
Chin et al., J Neurosci 2002 (Synaptic Transmission) : Treatment of pleural-pedal ganglia with TGF-beta1 for 5 min activated mitogen activated protein kinase ( MAPK ) and stimulated the phosphorylation of synapsin in a MAPK dependent manner
Giachello et al., J Cell Sci 2010 : However, the physiological role of MAPK/Erk dependent synapsin phosphorylation in regulating synaptic formation and function is poorly understood ... Our findings show that MAPK/Erk dependent synapsin phosphorylation has a dual role both in the establishment of functional synaptic connections and their short-term plasticity, indicating that some of the multiple extranuclear functions of MAPK/Erk in neurons can be mediated by the same multifunctional presynaptic target