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MAPK1 — SPRY2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: MAPK1 — SPRY2 (physical association, affinity chromatography technology) Egan et al., Proc Natl Acad Sci U S A 2002*

Text-mined interactions from Literome

Lee et al., Hepatology 2010 (Carcinoma, Hepatocellular...) : Sprouty2 (Spry2) , a negative feedback regulator of the Ras/mitogen activated protein kinase ( MAPK ) pathway, is frequently down-regulated in human hepatocellular carcinoma ( HCC )
Li et al., J Biol Chem 2013 (Breast Neoplasms...) : Forced expression of the miR-23a/24-2/27a cluster promoted mammary carcinoma cell migration, invasion, and hepatic metastasis, through targeting Sprouty2 (SPRY2) and consequent activation of p44/42 MAPK