◀ Back to ITGB2

ITGB2 — SELP

Pathways - manually collected, often from reviews:

• NCI Pathway Database amb2 Integrin signaling: P-selectin oligomer complex (SELP) → alphaM/beta2 Integrin/P-Selectin/PSGL1 complex (ITGAM-ITGB2-SELPLG-SELP) (modification, collaborate)
  Ma et al., Blood 2004*, Evangelista et al., Blood 1999*
  Evidence: mutant phenotype, assay
• NCI Pathway Database amb2 Integrin signaling: P-selectin oligomer complex (SELP) → alphaM/beta2 Integrin complex (ITGAM-ITGB2) (modification, collaborate)
  Ma et al., Blood 2004*, Evangelista et al., Blood 1999*
  Evidence: mutant phenotype, assay
• NCI Pathway Database amb2 Integrin signaling: alphaM/beta2 Integrin/P-Selectin/PSGL1 complex (ITGAM-ITGB2-SELPLG-SELP) → alphaM/beta2 Integrin complex (ITGAM-ITGB2) (modification, collaborate)
  Ma et al., Blood 2004*, Evangelista et al., Blood 1999*
  Evidence: mutant phenotype, assay
• NCI Pathway Database amb2 Integrin signaling: alphaM/beta2 Integrin/P-Selectin/PSGL1 complex (ITGAM-ITGB2-SELPLG-SELP) → PSGL1 (SELPLG) (modification, collaborate) Ma et al., Blood 2004*, Evangelista et al., Blood 1999*
  Evidence: mutant phenotype, assay
• NCI Pathway Database amb2 Integrin signaling: alphaM/beta2 Integrin/P-Selectin/PSGL1 complex (ITGAM-ITGB2-SELPLG-SELP) → Src Family Kinases-active (FGR/LYN/LCK/YES1/BLK/HCK/SRC/FYN) (leukocyte adhesion, collaborate)
  Piccardoni et al., Blood 2001
  Evidence: mutant phenotype, assay

Text-mined interactions from Literome

Zarbock et al., Immunity 2007 (Peritonitis) : Slow rolling on E-selectin coimmobilized with intercellular adhesion molecule-1 ( ICAM-1 ) required P-selectin glycoprotein ligand (PSGL)-1 , was dependent on alpha(L)beta(2) integrin ( LFA-1 ), and required continuous E-selectin engagement
Elstad et al., J Immunol 1995 : P-selectin did not stimulate increased surface expression of integrin CD11b/CD18 and did not enhance binding of iC3b coated erythrocytes, a CD11b/CD18 mediated functional response