Gene interactions and pathways from curated databases and text-mining

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IL10 — TYR

Text-mined interactions from Literome

Makuta et al., Biol Pharm Bull 2003 : In addition, IL-10 induced tyrosine (Tyr) phosphorylation of Erk, as well as serine ( Ser ) and Tyr phosphorylation of STAT-3
Qasimi et al., J Biol Chem 2006 : The SH2 domain, SOCS box, and both Tyr204 and Tyr221 were required for IL-10 inhibition of TNFalpha mRNA and protein expression, but interestingly the KIR domain was necessary only for IL-10 inhibition of TNFalpha protein expression
Wei et al., Cancer Immunol Immunother 2012 (Neoplasms, Experimental) : Both phospho-Ser9 and phospho-Tyr216 of GSK3ß were required for IL-10 expression induced by SCF/TLR4 ligand, whereas suppressive effect of SCF/TLR4 ligand on mast cell degranulation was related to phospho-Tyr216