◀ Back to HIF1A
HIF1A — TGFB3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Caniggia et al., J Clin Invest 2000
(Anoxia) :
Moreover, antisense inhibition of
HIF-1alpha expression in hypoxic explants
inhibited expression of
TGFbeta(3) , arrested cell proliferation, decreased alpha ( 5 ) expression and gelatinase A activity, and triggered biochemical markers of an invasive trophoblast phenotype such as alpha ( 1 ) integrin and gelatinase B expression
Caniggia et al., Placenta 2000
(Pre-Eclampsia) :
Antisense induced inhibition of
HIF-1alpha inhibited the expression of
TGFbeta3 , and stimulated extravillous trophoblast ( EVT ) outgrowth and invasion
McMahon et al., J Biol Chem 2006
(Inflammation) :
Among others, recent studies indicated that
transforming growth factor ( TGF ) beta increases the expression of the regulatory
HIF-1alpha subunit, and induces HIF-1 DNA binding activity