Gene interactions and pathways from curated databases and text-mining

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CPOX — EGF

Text-mined interactions from Literome

Kajanne et al., Pediatr Res 2007 : We tested the effect of EGF , hydrocortisone, and indomethacin on its activation, cell proliferation and migration, COX-2 expression, and prostaglandin E2 ( PGE2 ) production
Jia et al., Zhonghua Nan Ke Xue 2008 : To investigate the effect of PI-3K and p38MAPK signal pathways on the cyclooxygenase-2 (COX-2) expression induced by the epidermal growth factor (EGF) in PC-3 cells
Sabri et al., Cell Biochem Funct 2011 (MAP Kinase Signaling System) : Furthermore, EGF induced proliferation as well as EGF augmented COX2 expression was hindered by ERK1/2 and p38 inhibitors
Bany et al., Biol Reprod 1995 : In addition to IL-1 alpha, epidermal growth factor ( EGF, 40 ng/ml ) also caused a significant increase in PGE2 accumulation in the medium and COX activity in the cells ... The combined effects of IL-1 alpha and EGF on PGE2 accumulation and COX activity were additive
Sato et al., Prostaglandins 1997 (Carcinoma, Squamous Cell) : In addition, Northern blot analysis showed that the level of COX-2 mRNA was increased by the EGF-treatment, whereas no COX-2 mRNA was detected in the untreated cells, indicating that the EGF induced COX activity was resulted from the increase in the production of COX-2