Gene interactions and pathways from curated databases and text-mining

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CDK2 — ID1

Text-mined interactions from Literome

Wang et al., Mol Carcinog 2002 (Carcinoma...) : Ectopic Id-1 expression in CNE1 cells resulted in an increase in serum independent cell growth, percentage of cells in S phase, and phosphorylation of RB and cyclin dependent kinase 2 proteins
Hui et al., Int J Cancer 2006 (Carcinoma, Squamous Cell...) : However, overexpression of Id-1 had no effect on the pRB, CDK4 and p16INK4A expressions
Sharma et al., Cancer medicine 2012 : We propose that increased Id1 and Id3 expression attenuates all three cyclin dependent kinase inhibitors ( CDKN2B, -1A, and -1B ) resulting in a more aggressive PCa phenotype