◀ Back to CDK2
CDK2 — ID1
Text-mined interactions from Literome
Wang et al., Mol Carcinog 2002
(Carcinoma...) :
Ectopic
Id-1 expression in CNE1 cells
resulted in an increase in serum independent cell growth, percentage of cells in S phase, and phosphorylation of RB and
cyclin dependent kinase 2 proteins
Hui et al., Int J Cancer 2006
(Carcinoma, Squamous Cell...) :
However, overexpression of
Id-1 had no effect on the pRB,
CDK4 and p16INK4A expressions
Sharma et al., Cancer medicine 2012
:
We propose that increased
Id1 and Id3 expression
attenuates all three
cyclin dependent kinase inhibitors ( CDKN2B, -1A, and -1B ) resulting in a more aggressive PCa phenotype