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MAPK12 — PLCG2
Text-mined interactions from Literome
Kornmann et al., Gastroenterology 2002
(Cell Transformation, Neoplastic...) :
In vitro, TAKA-1 cells stably transfected with FGFR-1 IIIc exhibited increased basal growth ; enhanced basal tyrosine phosphorylation of FGFR substrate-2 (FRS2), Shc, and
phospholipase Cgamma ; and increased
activation of
mitogen activated protein kinase ( MAPK )
Chen et al., J Biol Chem 2002
:
Incubation of cells with the specific EGFR inhibitor AG4178 blocked MbetaCD induced phosphorylation of EGFR, SHC,
phospholipase C-gamma , and Gab-1 as well as
MAPK activation
Zheng et al., J Neurochem 2008
(Ion Channel Gating) :
Although previous studies suggested the roles of
mitogen activated protein kinase ,
phospholipase C-gamma mediated intracellular calcium ( [ Ca2+ ] i )
increase , and extracellular calcium influx in regulating Akt activation, the cellular mechanisms are largely unknown
Rho et al., J Pharmacol Exp Ther 1997
:
Involvement of
phospholipase C-gamma2 in activation of
mitogen activated protein kinase and phospholipase A2 by zooxanthellatoxin-A in rabbit platelets ... These results suggest that ZT-A stimulates a protein tyrosine kinase in the presence of external Ca++, resulting in the
activation of
MAPK probably via
PLC-gamma2 and protein kinase C