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BCL2 — CDH5
Text-mined interactions from Literome
Du et al., PLoS Biol 2007
(Adenoma, Islet Cell...) :
Although no changes were observed in rates of proliferation or apoptosis,
Bcl-xL altered cell morphology, remodeled the actin cytoskeleton, and
down-regulated cadherin 1 ; it also induced cell migration and invasion, as evaluated using two-chamber transwell assays
Zhao et al., Med Oncol 2012
(Melanoma) :
Hypoxia induced vasculogenic mimicry formation via
VE-cadherin regulation by
Bcl-2 ...
Bcl-2 overexpression
increased VE-cadherin expression and VM formation under normoxia, whereas Bcl-2 siRNA significantly decreased VE-cadherin expression and VM formation under hypoxia ... Therefore,
Bcl-2 dependent
VE-cadherin overexpression may be an important mechanism by which hypoxia induces VM