Gene interactions and pathways from curated databases and text-mining

◀ Back to BCL2

BCL2 — CDH5

Text-mined interactions from Literome

Du et al., PLoS Biol 2007 (Adenoma, Islet Cell...) : Although no changes were observed in rates of proliferation or apoptosis, Bcl-xL altered cell morphology, remodeled the actin cytoskeleton, and down-regulated cadherin 1 ; it also induced cell migration and invasion, as evaluated using two-chamber transwell assays
Zhao et al., Med Oncol 2012 (Melanoma) : Hypoxia induced vasculogenic mimicry formation via VE-cadherin regulation by Bcl-2 ... Bcl-2 overexpression increased VE-cadherin expression and VM formation under normoxia, whereas Bcl-2 siRNA significantly decreased VE-cadherin expression and VM formation under hypoxia ... Therefore, Bcl-2 dependent VE-cadherin overexpression may be an important mechanism by which hypoxia induces VM