Gene interactions and pathways from curated databases and text-mining

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HRAS — PCNA

Text-mined interactions from Literome

Teramoto et al., Oncogene 2003 : For example, H-Ras V12 upregulated osteopontin and Akt 1, and H-Ras and RhoA stimulated cyclin G1, cyclin dependent kinase 8, cyclin A2 and HMGI-C, while Rac1 QL and Cdc42 QL upregulated extracellular matrix and cell adhesion proteins such as alpha-actinin 4, procollagen type I and V and neuropilin
Minella et al., Proc Natl Acad Sci U S A 2005 : We show that oncogenic Ha-Ras activity regulates cyclin E degradation by the Fbw7 pathway