Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Musial et al., J Biol Chem 2001 : In contrast to proteasomal inhibitors, the calpain inhibitor calpastatin and the lysosomal inhibitors trans-epoxysuccinyl-l-leucylamido-4-guanidino butane, leupeptin, pepstatin-A, chloroquine, and NH ( 4 ) Cl did not lead to significant accumulation of iNOS
Cui et al., Am J Respir Cell Mol Biol 2005 : Involvement of calpain-calpastatin in cigarette smoke induced inhibition of lung endothelial nitric oxide synthase
Liu et al., Journal of inflammation (London, England) 2009 : Degradation of iNOS was reduced by a calpain inhibitor , suggesting that PIN1 may affect induction of other calpain-sensitive inflammatory proteins, such as cyclooxygenase (COX)-2, in MAEC
Griscavage et al., Biochem Biophys Res Commun 1995 : TPCK, TLCK, calpain inhibitor 1 (CPI-1) and calpain inhibitor 2 (CPI-2) each inhibited NOX- production and inducible iNOS expression in a concentration dependent manner at 1-100 microM