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IL4 — TNC
Text-mined interactions from Literome
Latijnhouwers et al., Arch Dermatol Res 2000
(Carcinoma, Basal Cell...) :
In contrast, TNF alpha favoured expression of smaller
tenascin-C transcripts, and
IL-4 equally
affected the expression of large and small tenascin-C mRNAs
Maqbool et al., Matrix Biol 2013
:
ECM-regulatory matricellular proteins are synthesized by several myocardial cell types including CF. We investigated the effects of pro-inflammatory cytokines on matricellular protein expression in cultured human CF. cDNA array analysis of matricellular proteins revealed that
interleukin-1a ( IL-1a, 10ng/ml, 6h ) down-regulated connective tissue growth factor ( CTGF/CCN2 ) mRNA by 80 % and
up-regulated tenascin-C (TNC) mRNA levels by 10-fold in human CF, without affecting expression of thrombospondins 1-3, osteonectin or osteopontin