Gene interactions and pathways from curated databases and text-mining

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FAS — IL10

Text-mined interactions from Literome

Daigle et al., Eur J Immunol 2000 (Inflammation) : Here we demonstrate that Fas receptor engagement results in the induction of the IL-10 gene in monocytes, but not in lymphocytes or dendritic cells
Watanabe et al., J Exp Med 2002 (Anemia) : In addition, serum levels of interleukin (IL)-10 significantly increased in Fas-/- x H+L6 homozygous mice and administration of anti-IL-10 Ab prevented exacerbation of autoAb production and AIHA
Yang et al., J Immunol 2003 (Glioma) : Cross linking of Fas with the agonistic Ab, CH-11, triggered apoptosis and enhanced the expression of IL-10 in Jurkat cells at the transcriptional and translational levels
Wang et al., World J Gastroenterol 2004 : To investigate the effects of platelet derived growth factor ( PDGF ) and interleukin-10 (IL-10) on Fas/Fas-ligand and Bcl-2/Bax mRNA expressions in rat hepatic stellate cells
Perl et al., Am J Pathol 2005 (Disease Models, Animal...) : Only Fas-siRNA markedly diminished lung tissue tumor necrosis factor-alpha, IL-6, IL-10 , interferon-gamma, IL-12, and caspase-3 activity
Zhang et al., World J Gastroenterol 2006 (Liver Cirrhosis) : The expression of Fas and FasL is increased in the course of liver fibrosis, and is further increased by IL-10
Zhang et al., Med Chem 2006 (Liver Cirrhosis) : The effects of interleukin-10 on the expression of Fas and FasL in rat hepatic stellate cells
Yamada et al., Diabetologia 1996 (Autoimmune Diseases...) : Mouse islet cell lysis mediated by interleukin-1 induced Fas