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CALM3 — FAS
Text-mined interactions from Literome
Ahn et al., Am J Pathol 2003
(Cholangiocarcinoma) :
Although a broad-range caspase inhibitor partially blocked CaM antagonist mediated apoptosis, the neutralizing Fas antibody had no effect, suggesting that
CaM antagonist mediated apoptosis does not
require interaction between CaM antagonists and surface
Fas
Suever et al., Biophys J 2008
:
In contrast, the
Fas mutant with the deletion of the 15 amino acid at the C-terminus
increased its binding to
CaM
Papoff et al., Biochim Biophys Acta 2010
:
Moreover, complementation experiments in Jurkat FADD-/- T cells indicated that : a ) cells expressing FADD mutants in the CaM binding sites are protected from Taxol induced G2/M cell cycle arrest ; b )
FADD/CaM interaction is not
required for
Fas receptor mediated apoptosis although Fas and CaM might compete for binding to FADD
Pan et al., Proteins 2011
:
We studied the interactions of different numbers of TFP molecules with CaM and explored the
effects of the resulting conformational changes in
CaM on
CaM-Fas binding