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EGF — SLC2A2
Text-mined interactions from Literome
Mischoulon et al., J Cell Physiol 1992
:
EGF, a potent liver mitogen, although causing a threefold induction of GLUT-1, was found to have no effect on GLUT-2 expression, suggesting that the increase in
GLUT-2 seen in regenerating liver is not
due to
EGF
Lee et al., Am J Physiol Gastrointest Liver Physiol 2006
(MAP Kinase Signaling System) :
Therefore, this study examined the
effect of
EGF on
GLUT2 and its related signal cascades in primary cultured chicken hepatocytes ... In addition, the
EGF induced decrease in
GLUT2 protein expression was inhibited by staurosporine, H-7, or bisindolylmaleimide I ( PKC inhibitors ), PD-98059 ( a MEK inhibitor ), SB-203580 ( a p38 MAPK inhibitor ), and SP-600125 ( a JNK inhibitor ), suggesting a role of both PKC and MAPKs ( p44/42 MAPK, p38 MAPK, and JNK )