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CTNNB1 — CYR61

Pathways - manually collected, often from reviews:

• NCI Pathway Database Regulation of nuclear beta catenin signaling and target gene transcription: beta catenin (CTNNB1) → CYR61 (CYR61) (transcription, activates) Si et al., Mol Cell Biol 2006*
  Evidence: reporter gene, physical interaction

Text-mined interactions from Literome

Xie et al., Cancer Res 2004 (Brain Neoplasms...) : Overexpression of Cyr61 also resulted in the phosphorylation of glycogen synthase kinase-3beta and accumulation and nuclear translocation of beta-catenin , leading to activation of the beta-catenin-TCF/Lef-1 signaling pathway
Tong et al., Oncogene 2004 (Carcinoma, Non-Small-Cell Lung...) : In addition, levels of both c-myc and beta-catenin increased in Cyr61 stably transfected H520 cells ... In this pathway, Cyr61 activated the beta-catenin/TCF4 complex, which promoted the expression of c-myc and the latter induced expression of p53, and p53 upregulated p21WAF1 and p130/RB2, resulting in growth arrest