◀ Back to CDKN1A

CDKN1A — SMARCB1

Pathways - manually collected, often from reviews:

• NCI Pathway Database Regulation of retinoblastoma protein: BRG1/BAF47 complex (SMARCA4-SMARCB1) → p21CIP1 (CDKN1A) (transcription, activates) Hendricks et al., Mol Cell Biol 2004*, Kang et al., Mol Cell Biol 2004*
  Evidence: mutant phenotype, reporter gene, physical interaction

Text-mined interactions from Literome

Wang et al., J Biochem 2007 : In this study, we show that BAF53 is involved in the repression of p53 dependent p21-gene transcription by interacting with p53 both in vivo and in vitro
Kuwahara et al., Cancer Res 2010 (Rhabdoid Tumor) : Our results show that both p21 ( CIP1/WAF1 ) and p16(INK4A) are targets for hSNF5 and that p21 ( CIP1/WAF1 ) upregulation during hSNF5 induced G ( 1 ) arrest precedes p16(INK4A) upregulation
Chano et al., PloS one 2010 (Neoplasms) : The nuclear RB1CC1 complex involving hSNF5 and/or p53 activated transcription of RB1, p16 and p21 , and suppressed tumor cell growth