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CCR1 — TGFB1
Text-mined interactions from Literome
Sato et al., J Immunol 2000
:
Stimulation of mature DCs with
TGF-beta 1 also
enhanced TNF-alpha induced down-regulation of the expressions of
CCR-1 , CCR-3, CCR-5, CCR-6, and CXCR-4, and chemotaxis to their respective ligands, while this stimulation suppressed TNF-alpha induced expression of CCR-7 and chemotactic migratory ability to MIP-3 beta
Han et al., Glia 2000
:
TGFbeta1 mediated increase of CCR1 mRNA accumulation
resulted in increased
CCR1 protein expression and augmented cell migration to a physiological ligand, macrophage inflammatory protein-1alpha ( MIP-1alpha ) ... The half life of CCR1 mRNA in the presence and absence of TGFbeta1 stimulation was comparable, suggesting that
TGFbeta1 induced
CCR1 mRNA accumulation occurred at the transcriptional level ...
TGFbeta1 did not
affect CCR1 mRNA expression in hematopoietic cells, indicating that TGFbeta1 effect on CCR1 expression in primary astrocytes is cell-type specific
Fifadara et al., Int Immunol 2009
:
CCR1 expression and signal transduction by murine BMMC
results in secretion of TNF-alpha,
TGFbeta-1 and IL-6