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BDNF — CCND1
Text-mined interactions from Literome
Yang et al., Cancer Res 2005
(Disease Models, Animal...) :
Administration of BDNF to tumor cell lines induced significantly increased expression of heat shock protein 90 (Hsp90) and cyclin D1, and blocking the activity of Hsp90 could reverse the up-regulation of
cyclin D1 induced by
BDNF
Simpson et al., Cell cycle (Georgetown, Tex.) 2007
(MAP Kinase Signaling System) :
Both NGF and
BDNF increase the expression of
cyclin D1 and cyclin dependent kinase 4 (cdk4), with temporal expression patterns that parallel the proliferation kinetics of their cellular targets