Gene interactions and pathways from curated databases and text-mining

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BCR — CD5

Text-mined interactions from Literome

Simarro et al., J Immunol 1999 : A-SMase, PKC-zeta, and MAPK family members are key mediators of cell responses as diverse as proliferation, differentiation, and growth arrest and may contribute to CD5 mediated modulation of TCR or BCR signaling
Gary-Gouy et al., J Immunol 2007 (Leukemia, Lymphocytic, Chronic, B-Cell) : Repeated BCR stimulation of normal B cells leads to anergy and CD5 expression, both of which are features of CLL
Sindhava et al., Frontiers in immunology 2012 : CD5 plays a major role in down regulation of BCR responses in the B-1a cell subset
Dennehy et al., Eur J Immunol 1998 : Both c-cbl and ras GAP have been proposed to suppress receptor mediated signaling, and may contribute to CD5 mediated suppression of TCR or BCR signaling