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CD274 — TNF
Text-mined interactions from Literome
Mazanet et al., J Immunol 2002
(Inflammation) :
B7-H1 is not expressed constitutively by ECs ; however, it is rapidly
induced by IFN-gamma, and synergistically by IFN-gamma and
TNF
Chen et al., Mol Immunol 2006
:
Flow cytometric analysis revealed that
B7-H1 but not B7-DC constitutively expresses on TECs, and the B7-H1 protein expression was profoundly
up-regulated by the stimulation of
TNF-alpha with a dose dependent manner
Kobayashi et al., J Rheumatol 2005
(Sjogren's Syndrome) :
In vitro analysis using HSG cells revealed that
PD-L1 was
induced by interferon-gamma but not by
tumor necrosis factor-alpha and IL-1beta
Nagamatsu et al., Hum Reprod 2009
:
B7-H1 blockade on DSCs strongly
enhanced T cell cytokine production ( IFN-gamma,
TNF-alpha and IL-2 ), whereas B7-DC blockade had similar but more modest effects
Ji et al., Hepatology 2010
(Liver Diseases...) :
These findings were confirmed in T cell-macrophage in vitro coculture in which
B7-H1Ig diminished
tumor necrosis factor-a/IL-6 levels in an IL-10 dependent manner
Ou et al., Scientific reports 2012
(Lupus Erythematosus, Systemic) :
Exogenous
TNF-a restored
PD-L1 expression on lupus monocytes