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TLR3 — TLR5

Text-mined interactions from Literome

Harii et al., Mol Endocrinol 2005 (Thyroiditis, Autoimmune...) : We conclude that functional TLR3 are present on thyrocytes ; TLR3 downstream signals can be overexpressed by pathogen related stimuli ; overexpression can be reversed by phenylmethimazole to a significantly greater extent than MMI by inhibiting only the IFN regulatory factor-3/IFN-beta/signal transducers and activation of transcription arm of the TLR3 signal system ; and TLR3 overexpression can induce an innate immune response in thyrocytes, which may be important in the pathogenesis of Hashimoto 's thyroiditis and in the immune cell infiltrates
Sel et al., J Immunol 2007 (Asthma...) : These data indicate that TLR-3 or TLR-7 activation by viral TLR ligands has both preventive as well as suppressive effects on experimental asthma which is mediated by the additive effects of IL-12 and IL-10
Deng et al., Circ Res 2009 (Disease Models, Animal...) : However, the architecture of the evolving inflammation is ligand-specific ; TLR4 ligands cause transmural panarteritis and TLR5 ligands promote adventitial perivasculitis
Charavaryamath et al., Gut microbes 2011 : Finally, Toll-like receptor (TLR)-4 expression was decreased but TLR-5 and -6 expression increased in ileal segments
Raicevic et al., Tissue Eng Part A 2012 : Inflammation was mimicked by a cytokine cocktail, and TLR activation was induced through TLR3 and TLR4 ligation
Deng et al., Immunol Cell Biol 2013 : The TLR signals that regulate the phagocytic ability of macrophages were also induced by TLR4 and TLR5 activation
Melkamu et al., Journal of cell communication and signaling 2013 : These findings demonstrate that TLR3 activation differentially regulates TLR expression through autocrine signaling involving IL-6 secretion, IL-6Ra activation and subsequent phosphorylation of Stat3