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IL21 — SOAT1
Text-mined interactions from Literome
Konforte et al., J Immunol 2006
:
Partial inhibition of
IL-21 induced
JAK/STAT signaling by the low-dose pharmacological agent, JAK inhibitor I, did not prevent the initial increase in proliferation ... Our study is the first to show the link between
IL-21 induced
JAK/STAT signaling, c-Myc regulation, and differentiation of human B cells
Strbo et al., AIDS 2008
(Chronic Disease...) :
The
effects of
IL-21 on perforin expression, proliferation, degranulation, interferon (IFN)-gamma production, cytotoxicity and induction of
STAT phosphorylation in NK cells were determined in vitro
Kaplan et al., Blood 2011
:
Thus,
STAT3 dependent
IL-21 production in T cells is required for HPC homeostasis
Imataki et al., J Immunol 2012
:
However,
STAT3 mediated
IL-21 signaling can supplement partial TCR signaling caused by the lack of CD8 association
Seidel et al., Proc Natl Acad Sci U S A 1995
(Carcinoma, Hepatocellular...) :
We have systematically examined the effects of the spacing between the TT and AA core half sites on the binding of the
STAT complexes
activated by IFN-gamma,
interleukin (IL) 6, granulocyte-macrophage colony stimulating factor, and IL-4