Gene interactions and pathways from curated databases and text-mining

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IL21 — SOAT1

Text-mined interactions from Literome

Konforte et al., J Immunol 2006 : Partial inhibition of IL-21 induced JAK/STAT signaling by the low-dose pharmacological agent, JAK inhibitor I, did not prevent the initial increase in proliferation ... Our study is the first to show the link between IL-21 induced JAK/STAT signaling, c-Myc regulation, and differentiation of human B cells
Strbo et al., AIDS 2008 (Chronic Disease...) : The effects of IL-21 on perforin expression, proliferation, degranulation, interferon (IFN)-gamma production, cytotoxicity and induction of STAT phosphorylation in NK cells were determined in vitro
Kaplan et al., Blood 2011 : Thus, STAT3 dependent IL-21 production in T cells is required for HPC homeostasis
Imataki et al., J Immunol 2012 : However, STAT3 mediated IL-21 signaling can supplement partial TCR signaling caused by the lack of CD8 association
Seidel et al., Proc Natl Acad Sci U S A 1995 (Carcinoma, Hepatocellular...) : We have systematically examined the effects of the spacing between the TT and AA core half sites on the binding of the STAT complexes activated by IFN-gamma, interleukin (IL) 6, granulocyte-macrophage colony stimulating factor, and IL-4