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CSF2 — SERPINE1

Text-mined interactions from Literome

Wohlwend et al., J Immunol 1987 : In cultures of resident peritoneal macrophages, phorbol myristate acetate and cholera toxin increase the synthesis of the Mr 55,000 secreted PAI, whereas dexamethasone decreases the synthesis of both PAI ; the production of PAI is also enhanced in the presence of macrophage colony stimulating factor ( CSF-1 )
Hamilton et al., Blood 1993 : Macrophage colony stimulating factor ( M-CSF or CSF-1 ) and granulocyte-macrophage CSF (GM-CSF) have been shown to increase human monocyte urokinase-type plasminogen-activator ( u-PA ) activity with possible consequences for cell migration and tissue remodeling ; because monocyte u-PA activity is likely to be controlled in part also by the PA inhibitors (PAIs) made by the cell, the effect of M-CSF and GM-CSF on human monocyte PAI-2 and PAI-1 synthesis was investigated ... Each CSF could enhance the protein and mRNA levels of PAI-2 and PAI-1 at similar concentrations for each product