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Ohata et al., FEBS Lett 2003
(Carcinoma, Hepatocellular...) :
In this study, we demonstrated that the expression of full HBV genome and HBx gene similarly stimulated the transcriptional activity of NF-kappaB in HuH-7 human hepatoma cells, and that interferon ( IFN ) -alpha as well as dominant negative mutant of IkappaB kinase-alpha effectively inhibited the HBx mediated NF-kappaB activation, but IFN-gamma did not
Kalvakolanu et al., Proc Natl Acad Sci U S A 1993
(Teratoma) :
We have recently shown that the adenovirus E1A gene products block interferon-alpha induced signal transduction and transcription factor NF-kappa B-mediated gene induction