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DUSP1 — RELA
Text-mined interactions from Literome
Wang et al., J Biol Chem 2008
:
Together, these results suggest that
MKP-1 is a
NF-kappaB mediated prosurvival effector in attenuating JNK mediated pro-apoptotic response ; NF-kappaB/MKP-1 mediated negative JNK regulation represents a potential therapeutic target for adjusting cell radiosensitivity
Bladh et al., Biochim Biophys Acta 2009
(MAP Kinase Signaling System) :
However, TPA treatment alone resulted in much stronger MKP-1 expression in both GRwt and GRR488Q containing cells than that of dexamethasone suggesting that the inability of GRR488Q to inhibit TPA induced
NF-kappaB activity did not
involve a lack of
MKP-1 expression
Wang et al., Mucosal Immunol 2010
:
Induction of
MKP-1 is
blocked by inhibitors of nuclear factor
(NF)-kappaB , but not of MAPK ... Thus,
NF-kappaB dependent expression of
MKP-1 may contribute, by desensitization of p38, to the rapid establishment of unresponsiveness to several TLR ligands in enterocytes