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CARD14 — RELA

Text-mined interactions from Literome

Koseki et al., J Biol Chem 1999 : Point mutations in highly conserved residues in the CARD of CIPER disrupted the ability of CIPER to activate NF-kappaB and to form homodimers, indicating that the CARD is essential for NF-kappaB activation and dimerization
Bertin et al., J Biol Chem 2000 : When expressed in cells, CARD9 binds to BCL10 and activates NF-kappaB
Bertin et al., J Biol Chem 2001 : When expressed in cells, CARD11 and CARD14 activate NF-kappaB and induce the phosphorylation of BCL10
Fontalba et al., J Immunol 2007 (Arthritis, Rheumatoid) : Thus, CARD8 may control NF-kappaB activation through a regulatory loop
Jordan et al., Am J Hum Genet 2012 (Arthritis, Psoriatic...) : CARD14 activates nuclear factor kappa B (NF-kB) , and compared with wild-type CARD14, the p.Gly117Ser and p.Glu138Ala substitutions were shown to lead to enhanced NF-kB activation and upregulation of a subset of psoriasis associated genes in keratinocytes