Zhang et al., J Biol Chem 2004
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Loss of PINCH-1 or ILK, to which alpha- and beta-parvin bind, significantly reduced the activation of Rac , a key signaling event that controls lamellipodium formation and cell spreading
Ito et al., Mol Biol Cell 2010
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We also show that PINCH-1 associates with Rsu-1 to activate Rac1 and that Rac1 activation is necessary for cell spreading