Gene interactions and pathways from curated databases and text-mining

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HAS1 — PDGFB

Text-mined interactions from Literome

Li et al., Biochem J 2007 : Analysis of HAS ( hyaluronan synthase ) and HYAL ( hyaluronidase ) mRNA expression showed that PDGF-BB treatment induced a 3-fold increase in the already high level of HAS2 mRNA, and increases in HAS1 and HYAL1 mRNA, whereas the levels of HAS3 and HYAL2 mRNA were not affected
Campo et al., Biochemistry (Mosc) 2007 : PDGF-BB induced HAS mRNA expression, protein synthesis, and HA production more efficiently than EGF and TGF-1beta
van Steensel et al., Invest Ophthalmol Vis Sci 2009 (Graves Ophthalmopathy) : Imatinib mesylate and AMN107 inhibited PDGF-BB induced orbital fibroblast proliferation, HAS induction and hyaluronan production by blocking PDGF-receptor phosphorylation