Gene interactions and pathways from curated databases and text-mining

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MMP14 — TCF4

Text-mined interactions from Literome

Sánchez-Tilló et al., Proc Natl Acad Sci U S A 2011 (Neoplasm Invasiveness) : Upregulation of MT1-MMP and LAMC2 by ß-catenin/TCF4 has been linked to invasiveness in CRCs, and we show here that both proteins are activated by ZEB1 coexpressing with it in primary colorectal tumors with mutated APC
Ma et al., J Biol Chem 2013 (Osteoarthritis, Knee) : Overexpression of TCF4 , but not of TCF3 or LEF1, induced MMP-1, -3, and -13 expression and generic MMP activity in human chondrocytes
Tyagi et al., J Mol Cell Cardiol 1997 : Results suggested that the increase in MMP promoter activity by heparin is due to a specific transcription factor binding to MMP-1 promoter sequence