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Wu et al., Atherosclerosis 1999
:
Enrichment of HAEC with the same doses of vitamin E suppressed
IL-1beta stimulated expression of intercellular adhesion molecule-1 ( ICAM-1 ), vascular cell adhesion molecule-1 ( VCAM-1 ), and endothelial leukocyte adhesion molecule-1 (
E-selectin )
Rudack et al., Allergy 2000
(Rhinitis, Allergic, Seasonal) :
The aim of the study was to determine the efficacy of a 30-min preincubation of the glucocorticosteroids (GCS) fluticasone, prednisolone, and fluocortin butyl on allergen- and interleukin
(IL)-1beta induced
E-selectin expression in allergic rhinitis
Rood et al., Eur J Clin Invest 2000
:
Upon
stimulation with
IL-1beta the expression of
E-selectin , VCAM-1 and ICAM-1 ( CD54 ) was upregulated ... The expression of
E-selectin and VCAM-1, which are not constitutively expressed on the cell lines, can be
induced by stimulation of the endothelial cells with
IL-1beta
Harcourt et al., J Interferon Cytokine Res 2000
:
Much higher levels of mRNA for interleukin-6 (IL-6), 2',5'-oligoadenylate synthetase ( 2',5'-OAS ), protein kinase ( PKR ), and interferon (IFN) regulatory factor-1 ( IRF-1 ) result from incubation with dsRNA than with IL-1beta, tumor necrosis factor-alpha (TNF-alpha), or IFN-alpha, whereas the differences in vascular cell adhesion molecule-1 ( VCAM-1 ), intercellular adhesion molecule-1 ( ICAM-1 ), and
E-selectin mRNA expression in
response to dsRNA,
IL-1beta , and TNF-alpha are relatively minor
Sharp et al., Inflammation 2001
(Inflammation) :
At 4 h ICAM-1 and
E-selectin , but not VACM-1, were
stimulated by both
IL-1beta and TNF-alpha ... ICAM-1, VCAM-1, and
E-selectin expression were all
stimulated by both
IL-1beta and TNF-alpha in the 24 h assays
Németh et al., Am J Physiol Cell Physiol 2002
:
NHE inhibition decreased also the IL-1beta induced HUVEC inflammatory response, because amiloride suppressed
IL-1beta induced
E-selectin expression on HUVECs
Piercy et al., J Surg Res 2002
:
Effects of estrogen, progesterone, and combination exposure on
interleukin-1 beta induced expression of VCAM-1, ICAM-1, PECAM, and
E-selectin by human female iliac artery endothelial cells
Evans et al., Endocrinology 2002
:
The activities of ERalpha and ERbeta were compared in three distinct gene regulatory pathways, including inhibition of
IL-1beta induction of
E-selectin expression, inhibition of basal endothelin-1 production, and the ability to induce two matrix stabilizing enzymes : tissue transglutaminase and a novel member of the lysyl oxidase family
Landis et al., Arthritis Rheum 2002
:
Human peripheral blood monocytes were differentiated for 1-7 days in vitro and examined with respect to 1 ) uptake of MSU crystals, 2 ) expression of macrophage, dendritic cell, and activation markers, 3 ) secretion of tumor necrosis factor alpha (TNFalpha),
interleukin 1beta (IL-1beta) , IL-6, and IL-10, 4 )
activation of endothelial
E-selectin expression, and 5 ) enhancement of secondary neutrophil recruitment by endothelial cells ... MSU crystals induced TNFalpha,
IL-1beta , and IL-6 ( but not IL-10 ) secretion in undifferentiated monocytes, which in turn
promoted endothelial cell
E-selectin expression and secondary neutrophil capture under shear flow
Gu et al., J Biol Chem 2003
:
The RelA-PR peptide blocked interaction of p47(phox) and RelA, and ectopic expression of RelA-PR abrogated
IL-1beta induced transactivation of the NF-kappaB dependent
E-selectin promoter ... Further, suppression of NADPH oxidase function through the inhibitor diphenylene iodonium, the superoxide dismutase mimetic Mn ( III ) tetrakis ( 4-benzoic acid ) porphyrin ( MnTBAP ), or expression of a dominant interfering mutant of a separate NADPH oxidase subunit ( p67 ( V204A ) ) decreased
IL-1beta induced
E-selectin promoter activation, suggesting that p47(phox) facilitates NF-kappaB activation through linkage with the NADPH oxidase
Chan et al., Cytometry A 2003
:
We have successfully applied the assays to evaluate ( a )
activation of
E-selectin ( CD62E ) expression by
interleukin-1beta in human umbilical vein endothelial cells ( HUVECs ), ( b ) induction of CD3 by phorbol-12-myristate-13-acetate in freshly prepared human peripheral blood lymphocytes, and ( c ) staurosporine induced apoptosis in HUVEC and normal human dermal fibroblasts
Sibson et al., Magn Reson Med 2004
(Encephalitis) :
Both TNF-alpha and
IL-1beta up-regulated
E-selectin on the brain endothelium, which correlated with increased signal intensity observed after administration of the novel contrast agent
Yu et al., Proc Natl Acad Sci U S A 2004
:
When
E-selectin was
induced by
IL-1beta , or lipopolysaccharide, human umbilical vein endothelial cells and human dermal microvascular endothelial cells each became markedly more sensitive to inhibition by endostatin in a vascular endothelial growth factor induced cell migration assay
Liu et al., Atherosclerosis 2004
(Arteriosclerosis) :
Pre-incubation of HAEC with AEM at 20 and 40 microg/ml, but not at 4 microg/ml, for 24h significantly suppressed
IL-1beta stimulated expressions of intracellular adhesion molecule-1 ( ICAM-1 ), vascular cell adhesion molecule-1 ( VCAM-1 ), and
E-selectin and the secretion of proinflammatory cytokines IL-6, chemokines IL-8 and monocyte chemoattractant protein (MCP)-1
Nascimento-Silva et al., Am J Physiol Cell Physiol 2005
(Acute-Phase Reaction) :
We demonstrate that treatment of EC with ATL-1 inhibited VCAM and
E-selectin expression
induced by TNF-alpha or
IL-1beta
Kang et al., Lab Invest 2006
:
CLIO-F ( ab ' ) ( 2 ) probes were administered via an i.v. injection following the
induction of
E-selectin expression by
IL-1beta ... Experiments in an adoptive transfer model demonstrated that HUVEC containing neovessels are perfused and that
IL-1beta inducible
E-selectin expression in these vessels is detectable with non-invasive imaging by using targeted nanoparticles
Sehnert et al., Arthritis Res Ther 2006
:
Concomitantly, ALP suppressed the
IL-1beta induced NF-kappaB activation and the
upregulation of
E-selectin expression in glEND.2 cells in vitro
Stannard et al., Arterioscler Thromb Vasc Biol 2007
(Atherosclerosis...) :
VEGF similarly enhanced
IL-1beta induced
E-selectin upregulation
Braham et al., J Periodontol 2009
:
A cytokine inactivation assay that measured
E-selectin expression in
response to TNF-alpha and
IL-1 beta was developed to measure the ability of aPDT to inactivate cytokine function
Lee et al., J Infect Dis 2010
(Inflammation...) :
In vitro activation of Toll-like receptor 2 (TLR2), up-regulated in ENL lesions, triggered induction of
IL-1beta , which together with interferon gamma
induced E-selectin expression on and neutrophil adhesion to endothelial cells
Yang et al., J Immunol 1994
(Sarcoma, Kaposi...) :
ICAM-1, VCAM-1, and
E-selectin were all
induced by dsRNA ( poly ( I:C ) ),
IL-1 beta , TNF-alpha, and LPS in KS cells
Tokushige et al., Laryngoscope 1994
(Chronic Disease...) :
These findings suggest that
IL-1 beta , one of mediators in chronic sinusitis, is produced by PMNs,
induces the expression of ICAM-1 and
ELAM-1 on endothelial cells, and, thereby, stimulates PMN infiltration in chronic sinusitis
Huang et al., Shock 1994
:
rBPI23 also prevented the LPS- but not
IL-1 beta induced upregulation on HUVEC of
E-selectin and CD54
Masamune et al., FEBS Lett 1995
:
N, N,N-trimethylsphingosine inhibits
interleukin-1 beta induced NF-kappa B activation and consequent
E-selectin expression in human umbilical vein endothelial cells ... We examined the effect of N, N,N-trimethylsphingosine ( TMS ) on the
interleukin-1 beta (IL-1 beta) induced
E-selectin expression in human umbilical vein endothelial cells ( HUVEC ) ... Incubation of HUVEC with TMS ( 0.1-10 microM ) resulted in a concentration dependent inhibition of
IL-1 beta induced
E-selectin expression
Wang et al., Atherosclerosis 1995
:
The
IL-1 beta induced expression of intercellular adhesion molecule 1 ( ICAM-1 ), vascular cell adhesion molecule 1 ( VCAM-1 ) and
E-selectin 1 ( ELAM-1 ) on SMCs was examined by reverse transcription/polymerase chain reaction ( RT/PCR )
Delomenie et al., Exp Cell Res 1993
:
Our results showed that
IL-1 beta , tumor necrosis factor (TNF)alpha, and MECIF activity
induced the expression of
ELAM-1 on HEC membrane while transforming growth factor beta ( TGF beta ), IL-6, and gamma-interferon ( IFN-gamma ) showed no effect
Klein et al., Pathobiology 1995
:
In previous studies, we have shown that
IL-1 beta and TNF alpha
increase the expression of
E-selectin and ICAM-1 on the cytoplasmatic membranes of HUVEC and human adult EC from the saphenous vein and femoral artery in a similar fashion
Del Papa et al., Arthritis Rheum 1996
(Wegener Granulomatosis) :
We found that AECA IgG from WG patients do not display any significant cytotoxicity but are able to up-regulate the expression of
E-selectin , intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 and to
induce the secretion of
IL-1 beta , IL-6, IL-8, and MCP-1
Goetz et al., Ann Biomed Eng 1996
(Colonic Neoplasms) :
Rolling KM12-L4 cells exhibit variable velocity motion over both
IL-1 beta stimulated HUVEC and
E-selectin-IgG1 chimera coated surfaces
Klein et al., Pathobiology 1995
:
In previous studies we have shown that
IL-1 beta and TNF-alpha
increase the expression of ICAM-1,
E-selectin and VCAM-1 on the cytoplasmatic membranes of HUVECs, HSVECs and HAFECs ( ECs from human umbilical vein, saphenous vein and femoral artery, respectively )
Rice et al., Anal Biochem 1996
:
The
effects of
IL-1 beta , TNF alpha, LPS, and an LPS conditioned plasma product on
E-selectin expression were characterized
Li et al., Int Arch Allergy Immunol 1997
:
Failure to block biosynthesis of
E-selectin and ICAM-1
induced by TNF-alpha and
IL-1 beta indicates the inhibitory effect exerted by serotonin was selective in nature
Nylander-Lundqvist et al., Acta Derm Venereol 1997
:
Whereas incubation mixtures with pro-IL-1 beta which had been incubated in the absence of SCCE, or with SCCE, which had been incubated in the absence of pro-Il-1 beta, did not induce expression above baseline levels of E-Selectin,
pro-Il1 beta which had been incubated with SCCE
induced a significant increase in
E-Selectin expression
Yoshida et al., Life Sci 1997
:
M-PSL also inhibited
IL-1beta induced upregulation of
E-selectin and ICAM-1 on HUVEC in a dose dependent manner
Kimura et al., J Ethnopharmacol 1997
:
Its 50 % inhibitory concentrations ( IC50 ) for the
IL-1 beta induced
ELAM-1 and ICAM-1 expressions were 2.3 x 10 ( -5 ) M and 4.0 x 10 ( -5 ) M, respectively ... In addition, protein C-kinase ( PKC ) inhibitor H7 also inhibited the
ELAM-1 and ICAM-1 expressions
induced by
IL-1 beta and TNF-alpha
Hirata et al., Am J Respir Cell Mol Biol 1998
(Lung Neoplasms) :
TNF-alpha and
IL-1beta increased the expression of ICAM-1,
E-selectin , and VCAM-1, whereas IL-4 induced only that of VCAM-1
Miller et al., J Leukoc Biol 1998
:
Utilizing neutralizing antibodies, we show that CD40L mediated tissue factor and thrombomodulin modulation, as well as
E-selectin and VCAM-1 upregulation, is
independent of tumor necrosis factor alpha, interleukin-1alpha, or
interleukin-1beta production
Heimbürger et al., Biochem Pharmacol 1998
:
Auranofin ( AF ) interacted with HUVEC and PMN adhesiveness but in opposite directions : this drug hampered
IL-1beta induced HUVEC hyperadhesiveness and expression of
E-selectin and intercellular adhesion molecule 1, but augmented PMN adherence and CD18 expression