Huang et al., PloS one 2011
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In contrast, ERK activation by MP1 is additive to that of KSR but it shows little ligand-sensitivity under high levels of EGF
Marina et al., Cell communication and signaling : CCS 2012
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Inhibition of MP1 expression in ER-positive MCF-7 cells did not affect ERK activity, but resulted in reduced Akt1 activity and reduced ER expression and activity
Schaeffer et al., Science 1998
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When overexpressed in cultured cells, MP1 enhanced activation of ERK1 and activation of a reporter driven by the transcription factor Elk-1 ... Expression of MP1 in cells increased binding of ERK1 to MEK1