Gene interactions and pathways from curated databases and text-mining

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CXCL12 — TNMD

Text-mined interactions from Literome

Ding et al., J Leukoc Biol 2000 : Monocyte chemotactic protein-1 (MCP-1), RANTES, and macrophage inflammatory protein-1alpha ( MIP-1alpha ) induced TEM by memory T cells, while stromal cell derived factor-1 (SDF-1) induced TEM by both naive and memory T cells
Kukreja et al., Cancer Res 2005 (Bone Neoplasms...) : SDF-1alpha increased PC-3 cell adhesion to the human umbilical vein endothelial cell monolayer and enhanced TEM , which was abrogated with anti-CXCR4 monoclonal antibody ( mAb )
Zabel et al., J Immunol 2009 : Importantly, although CXCL11 is unable to stimulate directly the migration of these cells, it acts as a potent antagonist of their CXCL12 induced TEM
Lee et al., J Leukoc Biol 2009 : Moreover, CXCL12 induced retro-TEM was inhibited by PI3K antagonism and cAMP agonism
Zabel et al., Molecular cancer 2011 (Lymphoma, B-Cell...) : In this study, we set out to assess the potential stimulation by CXCL12 of tumor cell TEM towards other chemokines and whether CXCR7 might be able to regulate such effects ... This CXCL12 potentiated TEM was inhibited by the second CXCR7 chemokine ligand, CXCL11 , as well as CXCR7-specific small molecule antagonists and antibodies
Lin et al., Eur J Immunol 1998 : These cells exhibited potent chemotaxis and TEM responses to the CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, RANTES, and monocyte chemotactic protein-3, and weak responses to the CC chemokine MIP-3beta and the CXC chemokine stromal cell derived factor (SDF)-1alpha