◀ Back to BCL2
BCL2 — CALM2
Pathways - manually collected, often from reviews:
-
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes:
CaM/Ca2+/Calcineurin A alpha-beta B1 complex (CALM2)
→
Calcineurin A alpha-beta B1/BCL2 complex (BCL2)
(modification, collaborate)
Kang et al., FEBS Lett 2005*, Weiwad et al., FEBS Lett 2005
Evidence: mutant phenotype, physical interaction
-
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes:
CaM/Ca2+/Calcineurin A alpha-beta B1 complex (CALM2)
→
FKBP38/BCL2 complex (FKBP8-BCL2)
(modification, collaborate)
Kang et al., FEBS Lett 2005*, Weiwad et al., FEBS Lett 2005
Evidence: mutant phenotype, physical interaction
-
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes:
Calcineurin A alpha-beta B1/BCL2 complex (BCL2)
→
CaM/Ca2+/FKBP38 complex (CALM2-FKBP8)
(modification, collaborate)
Kang et al., FEBS Lett 2005*, Weiwad et al., FEBS Lett 2005
Evidence: mutant phenotype, physical interaction
-
NCI Pathway Database Role of Calcineurin-dependent NFAT signaling in lymphocytes:
CaM/Ca2+/FKBP38 complex (CALM2-FKBP8)
→
FKBP38/BCL2 complex (FKBP8-BCL2)
(modification, collaborate)
Kang et al., FEBS Lett 2005*, Weiwad et al., FEBS Lett 2005
Evidence: mutant phenotype, physical interaction
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Erin et al., Neuroscience 2003
(Hypoxia-Ischemia, Brain) :
Experiments involving cell-free systems, as well as brain slices treated with thapsigargin or with N-methyl-D-aspartate suggested that calcium and
calmodulin activation of calcineurin
leads to interactions between calcineurin and
Bcl-2
Edlich et al., EMBO J 2005
:
Bcl-2 regulator FKBP38 is
activated by
Ca2+/calmodulin