Gene interactions and pathways from curated databases and text-mining

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ALOX5 — GPX7

Text-mined interactions from Literome

Hatzelmann et al., Eur J Biochem 1989 : Involvement of glutathione peroxidase activity in the stimulation of 5-lipoxygenase activity by glutathione depleting agents in human polymorphonuclear leukocytes ... At higher arachidonate concentrations and in the presence of Ca2+ the glutathione effect was not observed but additional glutathione peroxidase also blocked this maximally stimulated 5-lipoxygenase
Werz et al., Mol Pharmacol 1998 : Nonredox 5-lipoxygenase inhibitors require glutathione peroxidase for efficient inhibition of 5-lipoxygenase activity