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SLPI — WNT1

Text-mined interactions from Literome

Rawadi et al., J Bone Miner Res 2003 : The use of Noggin, a bone morphogenic protein ( BMP ) inhibitor, or cyclopamine, a Hedgehog inhibitor, revealed that the induction of ALP by Wnt is independent of these morphogenetic proteins and does not require de novo protein synthesis
Winkler et al., J Biol Chem 2005 : Dkk-1, a Wnt inhibitor, blocked Wnt induced ALP activity but not BMP induced ALP activity ... Sclerostin blocks Wnt induced ALP activity by blocking the activity of BMP proteins produced by Wnt treatment
Scheller et al., J Dent Res 2008 : Northern blot analysis found that Wnt-1 strongly induced the expression of matricellular protein osteopontin, and modestly enhanced the expression of type I collagen in DPSCs. Unexpectedly, Wnt-1 inhibited alkaline phosphatase (ALP) activity and the formation of mineralized nodules in DPSCs
Nemoto et al., Bone 2009 : Activation of endogenous canonical Wnt signaling with LiCl suppressed alkaline phosphatase (ALP) activity and expression of genes associated with cementum function ; ALP, bone sialoprotein ( BSP ), and osteocalcin ( OCN )
Jullien et al., J Cell Biochem 2012 (Wnt Signaling Pathway) : Pharmacological inhibition of Src signaling promoted ErbB3- and Wnt induced ALP activity, suggestive of a role of Src signaling in the modulation of osteoblast differentiation by ErbB3 and Wnt3a