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MYCN — TNFSF10

Text-mined interactions from Literome

Marengo et al., Free Radic Biol Med 2008 (Neuroblastoma) : It has been reported that neuroblastoma cells with MYCN amplification are unable to start TRAIL dependent death and MYCN , in concert with cytotoxic drugs, efficiently induces the mitochondrial pathway of apoptosis through oxidative mechanisms
Lutz et al., Oncogene 1998 (Neuroblastoma) : MycN also increased cell death in response to TRAIL and TNFalpha, suggesting that enforced MYCN expression in general increases the susceptibility of neuroblastoma cells towards a variety of death stimuli