Kamolmatyakul et al., J Dent Res 2001
(Bone Resorption) :
IL-6 and TNFalpha did not significantly affect cathepsin K gene expression in osteoclasts
Hou et al., Arthritis Rheum 2002
(Arthritis, Rheumatoid...) :
To determine and compare the expression of cathepsins K and S proteins in joints with rheumatoid arthritis ( RA ) and osteoarthritis ( OA ) and to determine the effect of interleukin-1 beta (IL-1 beta) and tumor necrosis factor alpha (TNF alpha) on the expression of cathepsin K in fibroblast-like synoviocytes ... The effect of IL-1 beta and TNF alpha on the expression and secretion of cathepsin K in primary cultures of synoviocytes was determined by real-time polymerase chain reaction and Western blot analysis