◀ Back to TNF
ADORA1 — TNF
Text-mined interactions from Literome
Johnston et al., Ann Neurol 2001
(Multiple Sclerosis) :
Previously, we have reported that the
adenosine A1 receptor ( A1AR )
regulates tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) expression and exhibits diminished function in patients with multiple sclerosis ( MS ; Mayne et al., Ann Neurol 1999 ; 45 : 633-639 )
Zhang et al., Biochem Pharmacol 2005
:
The
role of
adenosine A2A and A2B receptors in the regulation of
TNF-alpha production by human monocytes
Prabhakar et al., Int J Immunopharmacol 1995
:
We examined the
effects of
adenosine A1 and A2 receptor agonists on LPS stimulated
TNF alpha production by human monocytes isolated from peripheral blood
Lichtman et al., Hepatology 1994
:
Dibutyryl cyclic AMP, prostaglandin E1, prostaglandin E2 and the
adenosine A2-receptor agonist N-ethylcarboxyamideadenosine
inhibited lipopolysaccharide stimulated
tumor necrosis factor-alpha release by 83 %, 97 %, 90 % and 94 %, respectively, but inhibited peptidoglycan-polysaccharide stimulated tumor necrosis factor-alpha release by 52 %, 60 %, 45 % and 51 %, respectively ( p < 0.001 for each )