Gene interactions and pathways from curated databases and text-mining

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CLEC7A — TLR4

Text-mined interactions from Literome

Chaung et al., Vet Immunol Immunopathol 2009 : Zymosan enhanced dectin-1/TLR2/TLR4 expression and TNF-alpha/IL-10 production in all of three types of cell, whereas p-beta-glucan increased dectin-1/TLR4 and TNF-alpha/IL-12 production in AMs but inhibited IL-10 in mDCs
Zhu et al., Int Immunopharmacol 2013 (Disease Models, Animal...) : These findings demonstrated that ß-glucan activation of Dectin1/Syk attenuated LPS induction of TLR4/MyD88/NF-?B and inhibited the LPS induced inflammation factors in mammary epithelial cells, thereby providing a possibly protective effect of ß-glucan in the prevention of LPS induced dysfunction in mammary epithelial cells