Lokuta et al., Proc Natl Acad Sci U S A 2003
:
Further, both calpain inhibition and stimulation with IL-8 and formyl-Met-Leu-Phe ( fMLP ) induced an increase in Cdc42 and Rac activation
Fuhler et al., J Leukoc Biol 2005
(Myelodysplastic Syndromes) :
We then investigated IL-8 induced activation of the small GTPase Rac implicated in ERK1/2 dependent migration and found that it was less efficient in neutrophils from MDS patients compared with healthy donors