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Ruvolo et al., J Biol Chem 2008
(Precursor Cell Lymphoblastic Leukemia-Lymphoma) :
These results suggest that PKR regulates B56alpha mediated PP2A signaling in REH cells
Yao et al., Neuroscience 2010
(Memory Disorders) :
ECS also caused tau hyperphosphorylation at multiple Alzheimer related phosphorylation sites with activation of glycogen synthase kinase-3beta ( GSK-3beta ), Akt and phospho-PKR-like endoreticulum ( PERK ), and inhibition of protein phosphatase-2A (PP)-2A Cheng et al., Blood cancer journal 2013
:
Inhibition of PKR expression or activity reduces protein phosphatase 2A (PP2A) activity, a B-cell lymphoma 2 (Bcl-2) phosphatase, resulting in enhanced Bcl-2 phosphorylation