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IL1B — PLD2
Text-mined interactions from Literome
Chen et al., Diabetologia 1999
:
Interleukin-1beta increased the expression of adenine nucleotide translocator-1,
phospholipase D-1 and cytokine induced neutrophil chemoattractant-1 and decreased expression of the protein tyrosine phosphatase-like protein IA-2
Tong et al., J Mol Neurosci 1999
:
However, despite the ability of phorbol myristate acetate ( PMA ) to stimulate phospholipase D ( PLD ) and synthesis of phosphatidylethanol ( PEt ) in these cells,
PLD activity was not
affected by
IL-1beta
Chen et al., Endocrinology 2000
:
Interleukin-1beta regulates
phospholipase D-1 expression in rat pancreatic beta-cells ... RINm5F cells, but not primary beta-cells, expressed
PLD2 , and the expression of this gene was not
affected by
IL-1beta
Park et al., Mol Pharmacol 2002
:
The results of this study indicate that in human amnion cells,
IL-1 beta might
activate PLD through an upstream protein kinase C to elicit p38 and finally induce COX-2 expression